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https://www.matreya.com/search.aspx?keyword=1713
2-Hydroxy very long chain fatty acids are abundant in nervous tissues and are components of cerebrosides and sulfatides, which are mostly found in the myelin of nervous tissues. This alpha-hydroxy fatty acid contains an odd number of carbons and is much less prevalent than many other even-chain hydroxy fatty acids. It is therefore often useful as a standard or biomarker. 2-Hydroxytricosanoic acid has been reported in the marine sponge Amphimedon compressa.1 2-Hydroxy fatty acids are common in cosmetics and skin creams and lotions. 2- Hydroxy fatty acids are formed by the oxidation of saturated fatty acids by the enzyme fatty acid 2-hydroxylase. This enzyme is also responsible for the formation of 2-hydroxy galactolipids in the peripheral nervous system.2 alpha-Oxidation of 2-hydroxy fatty acids to CO2 and fatty acid occurs in the peroxisome and is unique from the alpha-oxidation of beta-carbon branched fatty acids such as phytanic acid. Cells from Zellweger syndrome and peroxisome-deficient cells are unable to undergo alpha-oxidation although patients with other peroxisomal disorders such as X-linked adrenoleukodystrophy, Refsum disease, and rhizomelic chondrodysplasia punctata are able.3 2-Hydroxy fatty acids are undergoing much research and various methods of analysis are being investigated.4
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名称: 深圳市明博林生物科技有限公司 税务登记号 9144030055718808X9 地址: 深圳市龙岗区布吉大芬村茂业城怡和楼2座8A 电话: 0755-25106053 开户银行: 中国工商银行深圳红宝支行 账号: 4000024839200103206
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